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Updated: Sep 15, 2025

Hybrid Cell Analysis System to Assess Structural and Contractile Changes of Human iPSC-Derived Cardiomyocytes for Preclinical Cardiac Risk Evaluation
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Hybrid Cell Analysis System to Assess Structural and Contractile Changes of Human iPSC-Derived Cardiomyocytes for Preclinical Cardiac Risk Evaluation

Published on: October 20, 2022

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人环素诱导心肌细胞染色质可访问性的全球变化,这些变化与心血管疾病的位置重叠

E Renee Matthews1, Raodatullah O Abodunrin2, John D Hurley3

  • 1Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, Texas, 77555, USA.

bioRxiv : the preprint server for biology
|July 16, 2025
PubMed
概括

像Anthracyclines (ACs) 这样的乳腺癌疗法可能会损害心脏. 这项研究揭示了这些药物如何改变心脏细胞基因调节,这可能解释了与遗传变异相关的心血管疾病 (CVD) 风险.

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