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Updated: Jul 7, 2026

Isolation of Specific Neuron Populations from Roundworm Caenorhabditis elegans
09:42

Isolation of Specific Neuron Populations from Roundworm Caenorhabditis elegans

Published on: August 6, 2019

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清除逆转神经元功能障碍在年轻人和老年人 C. 伊莱根斯 (elegans) 是一个词

T Carroll, G V W Johnson, K Nehrke

    bioRxiv : the preprint server for biology
    |July 16, 2025
    PubMed
    概括

    化陶在阿尔茨海默氏病 (AD) 中引起神经元功能障碍. 然而,去除陶蛋白逆转了虫中的这些缺陷,这表明与AD相关的神经元损伤可能是可逆的.

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    Modeling Age-Associated Neurodegenerative Diseases in Caenorhabditis elegans07:04

    Modeling Age-Associated Neurodegenerative Diseases in Caenorhabditis elegans

    Published on: August 15, 2020

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    In Vivo Quantification of Protein Turnover in Aging C. Elegans using Photoconvertible Dendra209:45

    In Vivo Quantification of Protein Turnover in Aging C. Elegans using Photoconvertible Dendra2

    Published on: June 13, 2020

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    In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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    Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
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    A revisionist approach to Jean Piaget's theory of cognitive development has brought new insights that challenge and reinterpret his established ideas. Piaget proposed that the formal operational stage, emerging in adolescence, represents the culmination of cognitive maturity. During this stage, individuals are said to develop abstract thinking, engage in systematic problem-solving, and show a form of egocentrism, believing others are as preoccupied with their behavior as they are themselves.