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Updated: Sep 15, 2025

Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor LATS Biosensor
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Published on: September 13, 2018

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SARS-CoV-2 NSP13与TEAD相互作用,以抑制Hippo-YAP信号传递

Fansen Meng, Jong Hwan Kim, Chang-Ru Tsai

    bioRxiv : the preprint server for biology
    |July 16, 2025
    PubMed
    概括

    严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 非结构蛋白13 (NSP13) 通过破坏河马通路来抑制YAP/TEAD介导的基因表达. 这种病毒蛋白向YAP的转录活性,影响器官的稳态和再生.

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