对的当前进展和未来方向的图书统计和可视化分析:从分子基础到治疗
Chengqiang Du1, Xinlei Xu2, Yehui Lv1
1School of Basic Medical Sciences, Institute of Wound Prevention and Treatment, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Frontiers in neurology
|July 16, 2025
概括
这项研究可视化了研究,强调了离子通道异常和神经炎症作为关键的分子标. 尽管取得了进展,但将基础科学发现与临床治疗联系起来仍然是一个挑战.
科学领域:
- 神经科学是一个神经科学.
- 遗传学 是一个遗传学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 病研究正在迅速发展,需要对其分子基础进行全面的概述.
- 了解分子基础对于开发有效的治疗策略至关重要.
研究的目的:
- 在研究的分子基础上对文献进行视觉分析.
- 为研究领域的学者和专业人士提供参考资料.
主要方法:
- 在Web of Science核心集合 (2015-2024) 中使用PubMed的MeSH术语进行文献搜索.
- 使用CiteSpace 6.2.2.使用CiteSpace 6.2.2.的1485篇获取文章的视觉分析. 这是R4软件.
- 分析出版趋势和引用数据.
主要成果:
- 确定了1485篇关于的分子基础的文章.
- 在出版物中观察到平均年增长率为14.41%.
- 根据趋势分析,预计2025年将有大约208个出版物.
结论:
- 离子通道异常 (例如,KCNQ2,SCN1A突变) 和神经炎症是当前基础研究的核心.
- 在基础研究发现 (circRNA,质神经元相互作用) 和临床应用之间存在差距.
- 新兴技术,如光遗传学和纳米药物输送需要进一步的临床验证.
相关概念视频
01:24Epilepsy and Seizures: Overview
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Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
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01:13Seizures: Classification
600
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
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