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TFAP2C通过转录调节影响PI3K/AKT/mTOR途径介导的EMT,以促进质母细胞瘤的发展

Shilin Li1, Kebo Liu1, Xiaoyang Li2

  • 1Department of Neurosurgery, Hunan University of Medicine General Hospital, Huaihua, China.

Cell biology international
|July 16, 2025
PubMed
概括

转录因子AP-2 (TFAP2C) 通过激活PI3K/AKT/mTOR通路来促进质母细胞瘤 (GBM) 的生长. TFAP2C直接结合PI3K促进体,为GBM治疗提供了潜在的治疗标.

关键词:
在PI3K/AKT/mTOR (PAM) 路径中.表皮质 - 介质细胞过渡 (EMT)质母细胞瘤是一种质母细胞瘤.转录因子AP-2马 (TFAP2C) 的转录因子转录规则 转录规则 转录规则

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