2008-2021年期间瑞典1型糖尿病的发生率
Yazan Al Abed1, Araz Rawshani1,2,3, Aidin Rawshani1
1Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
到2021年,1型糖尿病发病率在年轻人中增加了12%,发病率转移到年轻人. COVID-19 流行病可能影响了这一趋势,因此需要进一步调查SARS-CoV-2 的影响.
科学领域:
- 儿科 儿科 儿科
- 内分泌学 在内分泌学.
- 流行病学 流行病学
背景情况:
- 1型糖尿病 (T1D) 是一种慢性自身免疫性疾病,影响着世界各地的个人.
- 了解T1D发病率趋势和发病年龄对于公共卫生规划至关重要.
- COVID-19大流行对T1D发病率的影响需要仔细检查.
研究的目的:
- 从2008年到2021年,分析0-24岁个体的T1D发病率.
- 为了研究随着时间的推移,发病时年龄的变化.
- 评估COVID-19大流行对T1D发病率的潜在影响.
主要方法:
- 利用处方药注册表中的胰岛素处方数据来识别T1D病例.
- 根据处方频率确定T1D病例:男性1例或以上,女性3例或以上.
- 分为5年年龄组的分层发病率数据,用于整个研究期间的分析.
主要成果:
- 与2008-2019年平均水平相比,2021年0-24岁的T1D发病率增加了12%.
- 2021年,在0-4,5-9岁和20-24岁的年龄组中观察到的发病率最高.
- 发现了较年轻的发病年龄的显著趋势,流行病前的发病率稳定.
结论:
- 在2008年至2021年期间,观察到T1D发病年龄向年轻人转移.
- 2021年T1D发病率的上升可能与大流行期间SARS-CoV-2感染的延迟影响有关.
- 需要进一步的研究来证实大流行病在T1D发病率变化中的作用.
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