一项随机对照研究,以比较高频鼻腔氧化与常规氧气疗法在进行探索性腹腔切除术的患者中进行术后氧化疗法的有效性
Geetanjali T Chilkoti1, Poonam Sehrawat1, Medha Mohta1
1UCMS & GTB Hospital, Clinic of Anaesthesiology, Delhi, India.
高频鼻腔氧化 (HFNO) 在高风险腹部手术患者中改善了术后的氧化. 虽然氧化参数有所改善,但HFNO与常规疗法之间的并发症和其他变量仍然相似.
科学领域:
- 麻醉学 麻醉学
- 关键护理医学 关键护理医学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 手术后的肺部并发症 (PPC) 是发病率和死亡率的重要原因,特别是在长时间的上腹部手术后.
- 高频鼻腔氧化 (HFNO) 是一种在外科手术患者的抽管术后进行术后氧化的新方法.
研究的目的:
- 评估HFNO在改善腹部探索性手术中中度至高风险患者的氧化功效.
- 为了比较氧化参数,血液动力学稳定性和HFNO与常规氧气治疗之间的术后肺部并发症的发生率.
主要方法:
- 一个随机对照试验,涉及50名成年患者 (18-65岁) 的ARISCAT得分≥26接受探索性腹部手术.
- 随机分配患者接受常规氧气疗法 (C组) 或HFNO (H组) 输出管后.
- 氧化参数 (P/F比,PaO2,PaCO2,S/F比),血液动力学变量,PPC,急性缺血性呼吸衰竭 (AHRF),脱氧和舒适度得分在2,6,12和24小时后被记录下来.
主要成果:
- 与传统氧气疗法相比,HFNO显著改善了所有测量的氧化参数.
- 两组之间没有观察到PaCO2,血液动力学变量,整体并发症,PPC/AHRF的发病率或脱血症的显著差异.
- 患者舒适度得分也在两组之间相似.
结论:
- 在接受探索性腹部手术的中度至高风险患者中,HFNO的预防性使用可以改善术后的氧化.
- 在这种患者群体中,HFNO似乎是一种安全有效的选择,可以增强氧化,而不会增加不良事件.
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