在健康成年人中吞时喉体积和残留物的规范性参考值:使用320行区域探测器计算机断层扫描进行分析
Howell Henrian Bayona1, Yoko Inamoto2,3, Eiichi Saitoh4
1Graduate School of Health Sciences, Fujita Health University, Toyoake, Aichi, Japan.
Dysphagia
|July 16, 2025
概括
这项研究确定了健康成年人喉吞体积和残留物的参考值,发现年龄,性别,身高和球体特性影响了这些测量. 这些规范性数据有助于识别喉损伤.
科学领域:
- 吞生理学 吞生理学
- 定量成像分析分析 定量成像分析
- 生物机械工程 生物机械工程
背景情况:
- 喉吞对于营养摄入和呼吸道保护至关重要.
- 对喉功能进行定量评估对于诊断失消症至关重要.
- 喉吞参数的现有参考值是有限的.
研究的目的:
- 为了确定健康成年人吞时喉体积和残留物的规范性参考值.
- 为了研究年龄,性别,身高和球体特性对喉吞测量的影响.
- 为了提供一个比较具有和没有喉损伤的个体的基础.
主要方法:
- 用吞CT对135名健康日本成年人的288次吞进行了回顾性分析.
- 量化测量腔腔体积在玻尿酸保持 (PVHOLD),最大腔收缩 (PVMAX),腔体积收缩比率 (PVCR) 和吞后残留物.
- 用于动态3D-CT图像分析的半自动软件.
主要成果:
- 对于PVHOLD (20.9厘米3 [38.6厘米3]),PVMAX (0.3厘米3 [2.1厘米3]),PVCR (98.8% [89.1%]) 和残留物 (0厘米3 [0.4厘米3]) 的确定的规范值 (中位数[97.5百分比]).
- 男性表现出比女性更大的喉体积.
- 随着身高和年龄的增长,PVHOLD增加;随着较大,较厚的球体,PVMAX和PVCR增加.
- 喉残留与增加玻尿酸体积,年龄和更厚的玻尿酸一致性有关.
结论:
- 用吞CT确定了喉吞体积和残留物的规范性参考值.
- 人口统计因素和球体特性显著影响喉吞动态.
- 这些发现为临床评估和诊断喉吞障碍提供了定量基础.
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