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Updated: Sep 8, 2025

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探索从2-基化物衍生的希夫基作为潜在的抗癌剂:合成,表征,分子对接和体外评估

Oğuzhan Karaosmanoğlu1, Halil Berber2, Hülya Sivas3

  • 1Department of Biology, Faculty of Science, Eskişehir Technical University, Eskişehir, Turkey. Department of Biology, Kamil Özdağ Faculty of Science, Karamanoğlu Mehmetbey University, Karaman, Turkey.

Cell biochemistry and biophysics
|July 16, 2025
PubMed
概括

这项研究开发了新的希夫基作为潜在的抗癌剂. 化合物8S3通过破坏MAPK信号和线粒体功能,有效地诱导癌细胞的亡,为抗化疗耐药性提供了一个有前途的策略.

关键词:
这是一种抗癌药物.细胞亡活动.细胞毒性活动的细胞毒性.这就是MAPKK.有反应性氧物种的反应性氧物种.船舶基地是船舶的基地.

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