动脉样硬化斑块的热疗法使用超声波分相阵列系统
Sha Yuan1,2, Jiwen Hu3, Chuangjian Xia2
1School of Electrical Engineering, University of South China, Hengyang, 421001, China.
Medical & biological engineering & computing
|July 16, 2025
概括
聚焦超声波提供了一种新方法,可以安全有效地切除动脉样硬化斑块 (AP). 这项研究展示了一种阶段性阵列模型,用于精确的热除,保护周围组织.
科学领域:
- 生物医学工程 生物医学工程
- 医学物理 医学物理
- 心血管研究研究心血管研究
背景情况:
- 动脉样硬化斑块 (APs) 是一个重大的临床挑战.
- 目前对AP的治疗方法缺乏效率和安全性.
- 聚焦超声波的热效应为AP切除提供了潜在的可能性.
研究的目的:
- 提出和验证一种新的热除模式用于动脉样硬化斑块 (APs) 使用聚焦超声波.
- 为了研究一个单聚焦,可变频率扫描模型的疗效,用一个分相阵列用于AP治疗.
- 确保精确的能量定位和受控的加热,以安全有效地去除斑块.
主要方法:
- 为动脉样硬化斑块 (AP) 切除开发一个计算模型,结合流体-固体-热相互作用.
- 利用有限元法来解决复杂的并联热传递问题.
- 实现一个带有可变频率扫描模型的分相阵列系统,用于聚焦超声波传输.
- 采用一个闭环温度控制系统,设置为43°C,用于自动聚焦加热.
主要成果:
- 在模拟的动脉样硬化斑块 (AP) 中,声能在焦点的精确定位.
- 在精确的温度控制下 (43°C) 实现了自动聚焦加热,表明有效的热剥离.
- 展示了多次自动对焦扫描可以扩大废除区域,同时保留相邻的健康组织.
- 验证了模型处理不同深度和大小的斑块的能力.
结论:
- 提出的聚焦超声波热除模型为治疗动脉样硬化斑块 (APs) 提供了一种精确可控的方法.
- 这种方法通过保护周围的正常组织来提高治疗安全性.
- 变频扫描分相阵列模型为各种动脉样硬性斑块 (AP) 条件提供了一个有前途的治疗选择.
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