在内分泌部手术期间用于甲状腺检测的近红外自光:一项随机临床试验
Alexandria G Cousart1,2, Colleen M Kiernan3, Parker A Willmon1,2
1Vanderbilt Biophotonics Center, Vanderbilt University, Nashville, Tennessee.
JAMA surgery
|July 16, 2025
概括
基于纤维的近红外自光学 (NIRAF) 在甲状腺切除术和双侧甲状腺切除术期间改善了副甲状腺腺的识别. 这种技术提高了手术精度,而不增加手术时间,有助于保护甲状腺侧腺.
科学领域:
- 内分泌手术 内分泌手术
- 手术技术 手术技术
- 医疗成像医学成像
背景情况:
- 在甲状腺切除术和甲状腺切除术期间,准确地识别和保存副甲状腺腺 (PGs) 是非常重要的,以预防低副甲状腺症.
- 无意中损害PG可以导致严重的术后并发症.
研究的目的:
- 评估基于纤维的近红外自光 (NIRAF) 在增加手术内确定的PG的疗效.
- 为了确定NIRAF是否会在这些程序后降低低甲状腺功能障碍的发生率.
主要方法:
- 一个多中心随机临床试验,涉及752名接受甲状腺切除术或副甲状腺切除术的患者.
- 随机分配患者进行手术,使用或不使用基于纤维的NIRAF.
- 结果包括确定的PG数量和过渡性和永久性甲状腺功能低下症的发生率.
主要成果:
- NIRAF显著增加了在双边探索性副甲状腺切除 (3.5比3.2) 和甲状腺切除 (3.3比2.8) 期间发现的PG的平均数量.
- 在NIRAF和对照组之间没有观察到显著的甲状腺功能低下率差异.
- 使用NIRAF并没有增加手术的持续时间.
结论:
- 基于纤维的NIRAF是一种有价值的工具,可以在甲状腺切除术和双侧甲状腺切除术期间增强副甲状腺腺可视化.
- 这项技术可以通过增加PG识别而改善手术结果,而不会延长手术时间.
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