尺寸很重要:超声波成像和治疗中的微型与纳米泡
Mihir Sheth1,2, Caed Knight1, Qiang Wu1
1Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK.
Science advances
|July 16, 2025
概括
纳米泡本身不会产生强烈的声学信号. 它们明显的回声性往往是由于受到微泡污染,影响了超声波成像应用.
科学领域:
- 声学物理学的声学物理学
- 纳米技术纳米技术
- 生物医学成像学 生物医学成像学
背景情况:
- 与微气泡 (>1μm) 相比,纳米气泡 (<500nm) 的声学特性被研究.
- 了解纳米泡的回声性对于它们在医学成像和治疗中的应用至关重要.
研究的目的:
- 为了检查纳米气泡与微气泡的声学反应.
- 为了验证关于纳米泡回声性和行为的假设.
主要方法:
- 泡声学的理论建模.
- 使用超声波成像技术进行实验验证.
- 分析气泡大小分布和潜在污染.
主要成果:
- 只有一个假设得到了支持:显而易见的纳米泡回声性源于共存的微泡.
- 现有纳米粒子尺寸测量方法无法可靠地检测到现有的微气泡.
- 没有证据支持其他假设,尽管不能排除体内形成/胀.
结论:
- 归因于纳米泡的优异声响可能是由于微泡污染.
- 纳米泡在稳定性和药物输送方面可能有好处.
- 使用纳米泡来实现同等的成像/治疗效果需要更高的度,频率或强度.
相关概念视频
01:17Ultrasonography
6.2K
Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called...
During an ultrasonography procedure, a handheld device called...
6.2K
01:20Imaging Studies for Cardiovascular System II:Types of Echocardiography
398
Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
398