在急性缺血性中风患者中使用营养不良普遍查工具 (MUST) 对中风后食风险分层的实用性
Mayu Sasaki1, Hajime Ikenouchi2, Kei Nozue3
1Division of Nutrition Management, Sendai City Hospital, 1-1-1, Asuto-nagamachi, Taihaku-ku, Sendai, Miyagi 982-8502, Japan.
Clinical neurology and neurosurgery
|July 16, 2025
概括
营养不良普遍查工具 (MUST) 有效地识别了患有急性缺血性中风的患者,这些患者有高风险患中风后失足症 (PSD). 通过MUST进行早期查,可以进行主动管理,以获得更好的患者结果.
科学领域:
- 神经学 神经学
- 营养科学 营养科学
- 老年病的医生 老年病的医生
背景情况:
- 营养不良是已知的中风后食症 (PSD) 的风险因素.
- 营养查工具对PSD的预测价值尚未得到充分证实.
- 这项研究调查了PSD风险分层的营养不良普遍查工具 (MUST).
研究的目的:
- 评估营养不良普遍查工具 (MUST) 在分层化中风后食症 (PSD) 风险方面的有效性.
- 评估MUST在预测急性缺血性中风患者严重PSD (sPSD) 的性能.
主要方法:
- 796名急性缺血性中风患者的回顾性分析 (2018年1月至2020年12月).
- 根据功能性口服摄入量表 (FOIS) 定义的严重PSD (sPSD) 在第14天的得分≤3.
- 必须通过追溯评估;通过ROC分析和物流回归来评估性能.
主要成果:
- 19% (152/796) 的患者发生了sPSD.
- 在较高的MUST分数 (p<0.001) 时,sPSD患病率显著增加.
- 对于sPSD,MUST表现出强大的预测性能 (AUC=0.87),MUST ≥2显示97.4%的灵敏度和70.7%的特异性. 必须≥2独立地与sPSD相关 (aOR=4.93).
结论:
- 营养不良普遍查工具 (MUST) 对急性缺血性中风患者的PSD风险分层有效.
- 必须促进早期识别需要主动性消化障碍管理的患者.
- 使用MUST可以改善中风后的临床决策和患者护理.
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