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对A_m表型的血清学和秘书状况分析:来自印度东北部的两例病例

Joyisa Deb¹, Priyanka Gogoi¹, Gopal Krushna Ray¹

¹Department of Transfusion Medicine & Blood Centre, All India Institute of Medical Sciences, Guwahati, Assam 781101, India.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis

|July 16, 2025

概括

通过例行血液分组确定了两例罕见的Am表型,一个弱的A亚组. 详细的血清检测对于准确的ABO亚组鉴定至关重要,特别是在资源有限的环境中,确保输血安全.

科学领域:

免疫血液学免疫血液学
血型血清学血型血清学
遗传学遗传学是一个

背景情况:

血液分组中的II型ABO差异往往表明ABO亚组较弱.
Am表型是一种罕见的变体,其特征是弱A抗原表达.
报告像Am这样的罕见表型对于诊断准确性至关重要,特别是在获得先进的血清学工具有限的地区.

研究的目的:

报告在例行血液分组期间发现的两例Am表型病例.
突出与弱A子组相关的诊断挑战.
强调在资源有限的环境中进行详细的血清学检测的重要性.

主要方法:

常规的血液分组检查显示,在两个人身上存在II型ABO异常.
综合性免疫血液学检查包括常规管道技术,莱克的使用,变化温度,吸附-脱离研究和分泌剂测试.
机密者测试证实了唾液中A和H物质的存在.

主要成果:

吸附-脱离研究证实,在这两种情况下,A抗原表达弱.
秘测试结果与Am表型一致.
这些发现强调了识别弱A子组的复杂性.

结论:

详细的血清学测试对于准确的ABO亚组鉴定至关重要,特别是在缺乏分子诊断的资源有限的环境中.
正确识别像Am这样的罕见表型对于确保输血安全至关重要.
准确的识别可以防止错误分类,并改善患者的护理.

关键词:

A(m) 的子组.这就是ABO差异.吸附 - 脱离吸附-脱离第二种类型的 ABO 差异.弱点一个子组.

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