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Updated: Sep 15, 2025

Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation
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在人肝移植中,分辨不同类型的排斥的分子签名

Bastian Engel1, Ahmed Alaswad2, Alejandro Campos-Murguia3

  • 1Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany; PRACTIS & CORE100Pilot Clinician Scientist Programs, Dean's Office for Academic Career Development, Hannover Medical School, Hannover, Germany; MHH Transplant Center, Hannover Medical School, Hannover, Germany.

Journal of hepatology
|July 16, 2025
PubMed
概括

肝移植 (LT) 后的慢性抗体中介排斥 (cAMR) 有着独特的分子特征. 这种经常通过监测活检检测到的亚临床排斥与纤维化和移植失败的高风险有关.

关键词:
通过RNA测序进行RNA测序.通过T细胞介导的排斥所有移植拒绝拒绝通过抗体介导的排斥.慢性拒绝 慢性拒绝提供者特定的抗HLA抗体.乳腺上垂症 (ductopenia) 是一种干扰剂 干扰剂 干扰剂 干扰剂肝移植 肝移植 肝移植瘤死亡因子是瘤死亡因子.

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