落叶牙中的和以及婴儿养方法中的和:日本环境和儿童研究的出生队列辅助研究
Aya Hisada1, Yu-Ki Tanaka2, Akifumi Eguchi1
1Division of Environmental Preventive Medical Sciences, Center for Preventive Medical Sciences, Chiba University, Chiba, Japan.
The Journal of nutritional biochemistry
|July 16, 2025
概括
叶牙元素分析显示,婴儿养方法会影响 (Ba) 和 (Sr) 水平. 牙中Ba:Ca和Sr:Ca比率较高表明配方养与母乳养.
科学领域:
- 环境健康 环境健康
- 儿童营养学 儿童营养学
- 分析化学 分析化学
背景情况:
- 叶牙在胎儿和婴儿时期形成,作为元素暴露的独特历史记录.
- 了解牙的元素分布可以提供有关早期生活环境因素和营养状况的见解.
研究的目的:
- 调查婴儿养方法与 (Ba) 和 (Sr) 在落叶牙中的分布之间的联系.
- 探索出生季节与儿童牙中的元素比率之间的关系.
主要方法:
- 对216名儿童 (年龄为6~7岁) 的叶片状中央切口进行分析.
- 测量 (Ba), (Sr) 和 (Ca) 含量,使用激光除-诱导合等离子体质谱法.
- 使用多变量线性混合效应模型进行统计分析,以评估与养方法和出生季节相比的元素比率 (Ba:Ca, Sr:Ca).
主要成果:
- 与母乳养组相比,在配方养组中观察到更高的Ba:Ca和Sr:Ca比率,无论是在产前还是产后.
- 在夏天出生的儿童中,与冬天出生的儿童相比,发现了较高Sr:Ca比率的趋势.
- 该研究确定了养习惯和落叶牙中的元素度之间存在显著的关联.
结论:
- 树叶牙中的与 (Ba:Ca) 和与 (Sr:Ca) 的比率是估计婴儿养方法的潜在生物标志物.
- 叶状中心切口器作为评估从产前到产后发育的纵向元素暴露和营养状况的有价值指标.
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