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Updated: Sep 15, 2025

Dextran Enhances the Lentiviral Transduction Efficiency of Murine and Human Primary NK Cells
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基因转染的德克斯基载体:大自然的教训

Sara Masoumi Shahrbabak1, Vahid Tayebi-Khorrami2, Mohammad Reza Fadaei2

  • 1Department of Pharmaceutics, School of Pharmacy, Tehran University of Medical Science, Tehran, Iran.

International journal of biological macromolecules
|July 16, 2025
PubMed
概括

基于德克斯的基因传递系统为病毒载体提供了一种多功能且具有成本效益的替代方案. 化学修饰可以提高它们的性能,用于各种治疗应用,包括基因编辑.

关键词:
德克斯兰 (Dextran) 是一种基因输送 基因输送 基因输送修改后的德克斯.核酸转化过程中的核酸转化过程多重复合的多重复合体.一个质子海绵.

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Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
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