作为抑郁症,焦虑症和物质使用的风险因素,低于值的躁狂症状:在一般人口中进行的一项前性研究的结果
Rosalie A L Beekman1, Margreet Ten Have2, Ron de Graaf2
1Altrecht Institute for Mental Health Care, Utrecht, the Netherlands; Amsterdam University Medical Center, Vrije Universiteit, Department of Psychiatry and Amsterdam Public Health Research Institute, Amsterdam, the Netherlands.
Journal of affective disorders
|July 16, 2025
概括
低值躁狂症状 (subM) 显著增加患抑郁症,焦虑症和双极性疾病 (BD) 的风险. 早期识别subM对于预测和预防这些常见的精神障碍至关重要.
科学领域:
- 精神病学是一个精神病学.
- 流行病学 流行病学
- 心理健康研究 心理健康研究
背景情况:
- 像抑郁症和焦虑症这样的常见精神障碍 (CMD) 会导致严重的疾病负担.
- 指示的预防针对的是高风险的个体,他们的症状低于值.
- 低值躁狂症状 (subM) 被研究为CMD和双相情感障碍 (BD) 的潜在危险因素.
研究的目的:
- 作为常见精神障碍 (CMD) 和双相情感障碍 (BD) 的风险因素,调查下值躁狂症状 (subM).
- 评估一般人口队列中三年CMD表现和BD发病的情况.
主要方法:
- 在3年内对4618名成年人进行了评估,这些成年人代表了荷兰一般人口.
- 亚M被定义为至少四天的情绪升高或易怒,不符合全部BD标准.
- 记录了明显的CMD和发病BD,在基线上没有CMD,在基线和终身中没有BD.
主要成果:
- 患有subM的个体显著增加了明显抑郁症 (OR 2.3-2.9) 和焦虑症 (OR 1.5-5.9) 的风险.
- 患有双相情感障碍 (BD) 的风险在亚M (OR 6.4-43.8) 个体中显著增加.
- 这些增加的抑郁,焦虑和BD风险在调整社会人口统计学,临床和生活方式因素后仍然存在.
结论:
- 门以下躁狂症状 (subM) 是即将出现的抑郁症,焦虑症和双相情感障碍的显著短期预测因素.
- 在情绪和焦虑障碍的精神病学途径中,SubM应该被认为是相关的预测因素.
- 建议包括将subM纳入风险预测工具和情绪和焦虑障碍的预防干预.
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