慢性病患者疲劳的患者报告结果措施:系统性审查
Anastasia Hughes1,2, Angela Ju3,2, Rosanna Cazzolli3,2
1Sydney School of Public Health, The University of Sydney, Sydney, New South Wales, Australia anastasia.hughes@sydney.edu.au.
BMJ open
|July 16, 2025
概括
慢性病 (CKD) 疲劳的患者报告的结果措施差异很大. 很少有针对CKD的具体措施,并且强大的心理测量数据有限,这凸显了需要更好的评估工具的需要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 临床流行病学 临床流行病学
- 患者报告的结果
背景情况:
- 疲劳是慢性病 (CKD) 患者中常见且严重的症状,这些患者没有接受置换疗法 (KRT).
- 它显著增加了死亡,透析启动和住院的风险.
- 精确测量疲劳对于患者管理和研究至关重要.
研究的目的:
- 系统地审查患者报告的结局措施 (PROMs) 对于未透析的CKD患者的疲劳.
- 确定这些疲劳评估工具的特征,内容领域和心理特征.
- 为了评估现有的PROMs适合在这个特定的患者群体中测量疲劳.
主要方法:
- 进行了对文献的系统审查.
- 在主要数据库 (MEDLINE,Embase,PsycINFO,CINAHL) 进行了搜索,截至2023年2月.
- 包括不接受KRT的1-5阶段CKD患者的研究,提取PROM特征和心理测定验证数据.
主要成果:
- 确定了27种不同的PROM,其中SF-36和KDQOL-SF是最常见的.
- 只有6个PROM是特定于疲劳的;大多数包括疲劳作为更广泛措施的一部分.
- 专门针对CKD开发的措施很少,有限的数据支持了这个人群中大多数疲劳PROM的心理特征.
结论:
- 现有的用于非透析CKD患者疲劳的PROM缺乏特异性和内容相关性.
- 支持这些措施的心理测量证据通常很少.
- 显然需要一个经过验证和内容适当的PROM来准确评估CKD患者的疲劳.
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