免疫球蛋白E介导的食物过敏的诊断
Chloe Opper1, Megan Bannon1, Ashley L Devonshire1
1Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati School of Medicine, Cincinnati, OH, USA.
数以百万计的人患有免疫球蛋白E介导的食物过敏. 本综述涵盖了当前的食物过敏 (FA) 诊断测试以及更好的患者风险评估和管理的新兴进展.
科学领域:
- 过敏和免疫学 过敏和免疫学
- 临床诊断 临床诊断 临床诊断
背景情况:
- 免疫球蛋白E (IgE) 介导的食物过敏是全球重要的健康问题,影响数百万.
- 准确的诊断和对食物过敏和相关表型的理解对于有效的患者护理至关重要.
- 目前对食物过敏的诊断方法需要仔细评估其性能.
研究的目的:
- 审查目前可用的食品过敏诊断测试模式的性能.
- 突出最近在食品过敏诊断测试领域取得的进展.
- 讨论新型诊断对食品过敏风险评估,表型和管理的潜在影响.
主要方法:
- 对评估食物过敏诊断测试研究的文献综述.
- 对现有的食物过敏诊断模式的性能指标的分析.
- 识别和汇总新兴技术和食品过敏诊断方面的进展.
主要成果:
- 目前的食物过敏诊断测试在性能特征上有所不同.
- 一些新的诊断方法正在出现,它们有可能提高准确性.
- 进展可能会导致更精确的患者表型和量身定制的管理策略.
结论:
- 目前的食物过敏诊断测试的执行需要持续的研究和开发.
- 新型诊断工具有望提高风险评估和患者分层的准确性.
- 预计未来的诊断进展将显著改善对食物过敏的临床管理.
更多相关视频
10:27Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
06:34A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
Published on: June 4, 2017
相关概念视频
Antibody Structure
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Enzyme-Linked Immunosorbent Assay
There are many different types of ELISAs, but they all involve an antibody molecule whose constant region binds an enzyme, leaving the variable region free to bind its specific antigen. Enzyme-substrate reaction allows the antigen to be visualized or...
Allergic Reactions
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
