口服食物挑战:诊断的标准
Jessica Macdougall1, Devangi Shah2, J Andrew Bird3
1Department of Pediatric Allergy and Immunology, Oregon Health and Science University, OHSU Physicians Pavilion, 3270 SW Pavilion Loop, Portland, OR 97239, USA.
Immunology and allergy clinics of North America
|July 16, 2025
概括
口服食物挑战是诊断食物过敏的黄金标准,但成本高且有风险. 在这些必要的诊断过程中,标准化的协议和培训对于患者的安全至关重要.
科学领域:
- 临床免疫学和过敏诊断.
- 食物过敏性研究.
背景情况:
- 口服食物挑战 (OFC) 是诊断食物过敏的绝对方法.
- OFC指导食品重新引入或继续避免的决策.
- 目前的OFC是资源密集型,耗时,并带有固有的风险.
研究的目的:
- 突出口服食品在临床实践中的关键作用.
- 强调对执行OFCs的标准化协议和适当培训的需要.
- 强调管理与OFC相关的风险的重要性.
主要方法:
- 对当前临床实践和有关口服食品挑战的文献的审查.
- 讨论与OFCs相关的限制和风险.
- 探索替代生物标志物在过敏管理中的作用.
主要成果:
- 口服食物挑战仍然是食品过敏诊断的黄金标准.
- 替代生物标志物虽然有用,但不能替代OFCs.
- 开支,时间承诺和OFC的潜在风险是重要的考虑因素.
结论:
- 标准化的协议和全面的培训对于安全有效的口服食品挑战至关重要.
- 在OFC期间最大限度地降低风险对于患者的福祉至关重要.
- 持续依赖OFCs需要在临床环境中采取强有力的安全措施.
相关概念视频
Serum Laboratory Studies, Stool Test, Breath Test
476
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
476
Taste Buds and Receptors
2.8K
Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
2.8K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
426
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
426
What is Monogastric Digestion?
72.5K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
72.5K


