一个由尿路炎引发的尿的病例在olanzapine诱导的糖尿病酸症中
Hideyuki Murakami1, Kazuaki Norita1, Akihiro Ikeda1
1Internal Medicine, Ashoro National Health Insurance Hospital, Japan.
Internal medicine (Tokyo, Japan)
|July 16, 2025
概括
本案例研究强调了抗精神病药物 olanzapine 如何在精神分裂症患者中导致糖尿病酸性糖尿病和尿. 迅速治疗解决了患者的症状,强调了药物的副作用.
科学领域:
- 药理学 药理学是指药理学的学科.
- 内分泌学 在内分泌学.
- 精神病学是一个精神病学.
背景情况:
- 精神分裂症的治疗通常涉及抗精神病药物.
- 奥兰沙平是一种常见的非典型抗精神病药物.
- 抗精神病药物的副作用需要仔细监测.
研究的目的:
- 报告糖尿病酸性和尿的病例,可能与奥兰zapine相关.
- 审查抗精神病药物,代谢障碍和泌尿功能之间的关系.
- 提高人们对奥兰zapine罕见但严重的副作用的认识.
主要方法:
- 一个58岁的精神分裂症女性患者的病例报告.
- 临床检查,实验室检查和尿液分析.
- 关于抗精神病药物引起的并发症的文献综述.
主要成果:
- 患者表现出意识受损,腹部张张,糖尿病酸性脂肪酸症和尿液保留.
- 尿道导管和血糖控制后症状有所改善.
- 确定了olanzapine作为潜在的病理生理学贡献因素.
结论:
- 抗精神病药物,特别是 olanzapine,可能与严重的代谢和尿道并发症有关.
- 早期识别和管理对于患者的治疗结果至关重要.
- 需要进一步的研究来阐明正确的机制,将奥兰扎与这些不良事件联系起来.
相关概念视频
Acute Kidney Injury III: Clinical Manifestations
96
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
96
Disorders of the Urinary System
489
The urinary system is responsible for eliminating waste and excess fluids from the body. However, disorders of the urinary system can arise due to various reasons like infections, stress, age, congenital abnormalities, and lifestyle.
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
489
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
42
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
42
Urinary Tract Calculi V: Nursing Management
31
AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...
31
Urinary Tract Calculi III: Medical Management
27
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
27
Urinary Tract Infection IV: Nursing Management
89
In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs...
89


