新生儿出生时腹壁缺陷的严重先天性心脏缺陷的患病率
Zane J Hellmann1, Linh Buu1, Shahyan Rehman1
1Yale New Haven Children's Hospital, New Haven, Connecticut, USA.
Prenatal diagnosis
|July 16, 2025
概括
患有胃的婴儿有明显更高的临界先天性心脏缺陷 (CCHD) 的风险. 这种组合导致心脏手术和新生儿重症监护室 (NICU) 入院期间死亡率增加.
科学领域:
- 新生儿科学 新生儿科学
- 儿童心脏病学 儿童心脏病学
- 遗传异常是一种先天性异常.
背景情况:
- 胃分裂是一种主要的先天性异常,对新生儿的结果有重大影响.
- 在患有胃症的婴儿中,严重先天性心脏缺陷 (CCHD) 的同时发生尚未得到充分证实.
- 这项研究调查了新生儿中CCHD的患病率和影响.
研究的目的:
- 为了确定患有胃症的婴儿中心血管疾病的患病率.
- 评估新生儿在新生儿重症监护室 (NICU) 入院期间患有胃和CCHD的新生儿的结果.
主要方法:
- 利用美国卫生和人类服务部的数据来确定胃,腹和心血管疾病的活产率.
- 分析了2017-2023年儿童健康信息系统 (PHIS) 数据,用于使用ICD-10代码的NICU住院患者.
主要成果:
- 患有胃的婴儿显示CCHD的患病率明显更高 (OR = 8.18).
- 在NICU入院期间,患有胃和CCHD的新生儿经历了开放心脏手术 (OR = 12.20) 和死亡率 (OR = 9.56) 的增加.
结论:
- 患有胃的婴儿被诊断出患有心血管疾病的可能性要高得多.
- 胃和CCHD的联合诊断与较差的结果有关,包括心脏手术和新生儿重症监护室死亡率的较高.
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