在患有或没有2型糖尿病的成年人中,急性有氧运动后血管功能
João Luís Marôco1,2, Inês Arrais2,3, Tiago Silvestre2,4
1Integrative Human Physiology Laboratory, Manning College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, MA, USA.
Scientific reports
|July 16, 2025
概括
2型糖尿病 (T2DM) 在炼后改变血管功能. 高强度间歇运动 (HIIE) 和中等强度连续运动 (MICE) 都会暂时改变T2DM老年人的血管反应.
科学领域:
- 心血管生理学心血管生理学
- 代谢性疾病研究研究
- 运动科学 运动科学
背景情况:
- 2型糖尿病 (T2DM) 与血管功能障碍有关.
- 不同强度的有氧运动对T2DM患者血管功能的影响尚不清楚.
研究的目的:
- 研究T2DM对动脉流介导扩张 (FMD) 和高强度间歇运动 (HIIE) 和中等强度连续运动 (MICE) 后脉冲波速度 (PWV) 变化的影响.
- 为了比较急性运动干预后T2DM和没有T2DM的成年人之间的血管反应.
主要方法:
- 参与者包括患有T2DM的老年人和健康的年轻人和老年人.
- 通过在运动后10分钟和60分钟测量手臂动脉流介导扩张 (FMD) 和脉冲波速度 (PWV) 的流介导减速 (FMS) 来评估血管功能.
- Carotid-femoral脉冲波速度 (cfPWV) 用于估计中心动脉硬度.
主要成果:
- 在患有T2DM的成年人中,HIIE在10分钟后急剧减少了FMD%和增加了FMS%,反应在60分钟后正常化.
- 在患有T2DM的成年人中,MICE在10分钟后急剧增加了FMD%.
- 在HIIE或MICE之后的任何组中都没有观察到cfPWV的显著变化.
结论:
- 有氧运动,无论是HIIE还是MICE,都会在患有T2DM的老年人中引起暂时的血管功能改变.
- 这些发现表明,T2DM患者对急性有氧运动的疾病特异性血管反应.
- 了解这些短暂的变化对于优化T2DM患者的运动处方至关重要.
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