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使用纵向临床体重指数对儿童肥胖的分类及其验证
Nia Ebrahim1, Apruva Khadegi2, Shuliang Deng3
1Institute of Human Nutrition, Columbia University, New York, NY, 10032, USA.
International journal of obesity (2005)
|July 16, 2025
概括
一个新的儿童纵向体重指数 (BMI) 分类比传统的横截面BMI更好地预测长期心脏代谢风险. 这种方法有助于针对儿童肥胖的有针对性的干预措施.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 心血管健康 心血管健康
- 肥胖问题研究研究
背景情况:
- 儿童肥胖与长期心脏代谢风险有关.
- 目前的肥胖症分类依赖于横截面的身体质量指数 (BMI) 百分点.
- 需要更动态的分类来捕捉持续性肥胖和相关风险.
研究的目的:
- 开发和验证儿童的纵向BMI分类系统.
- 评估这种新分类与早期肥胖,社会经济地位和心脏代谢风险的关联.
- 为了比较纵向与横截面BMI对心脏代谢风险的预测能力.
主要方法:
- 利用来自大型第三级护理医院和独立队列的电子健康记录数据.
- 在纵向分类中使用的BMI百分位数中位数和肥胖类的持久性 (≥3个BMI测量).
- 分析了纵向BMI类别,早期肥胖,社会经济地位 (SES) 和心脏代谢风险指标之间的关联.
主要成果:
- 肥胖 (BMI ≥95百分位数) 影响24.1%的儿童,严重肥胖10.6%.
- 早期发病的肥胖症 (≤6年) 通常持续存在,较高的SES与较低的肥胖率有关.
- 纵向BMI分类显示,与横截面BMI (75.8%) 相比,心脏代谢风险 (AUC 80.0%) 的预测优越.
结论:
- 纵向的BMI分类提供了一个更准确的反映儿童的长期心脏代谢风险.
- 这种精细的分类可以指导有针对性的干预措施,并确定儿童的遗传风险概况.
- 这些发现支持在儿童肥胖管理中转向动态BMI评估.
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