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Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells
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Published on: February 8, 2018

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治疗抗PD-1-耐药高级黑色素瘤的挑战

Cecilie Dam Vestergaard1, Eva Ellebaek1, Troels Holz Borch1

  • 1Department of Oncology, National Center for Cancer Immune Therapy, Copenhagen University Hospital, Borgmester Ib Juuls Vej 9, 4th Floor, 2730, Herlev, Denmark.

American journal of clinical dermatology
|July 16, 2025
PubMed
概括

免疫检查点抑制剂可以改善转移性黑色素瘤的结果,但超过一半的患者会产生耐药性. 本综述探讨了抗PD-1治疗进展的患者的抗药性机制和新疗法.

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