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Updated: Sep 15, 2025

Visualization of Inflammatory Caspases Induced Proximity in Human Monocyte-Derived Macrophages
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卡迪奥利平通过阻止LPS与-4/11酶结合来抑制非正规性炎症酶

Malvina Pizzuto1,2,3, Mercedes Monteleone4, Sabrina Sofia Burgener4

  • 1Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, 4072, Australia. m.pizzuto@uq.edu.au.

The EMBO journal
|July 16, 2025
PubMed
概括

线粒体心脏脂蛋白选择性地抑制酶-4/11 (CASP4/11) 以阻止脂多糖 (LPS) 诱导的炎症. 这一发现为研究CASP4/11和开发LPS相关疾病的治疗方法提供了新的工具.

关键词:
卡迪奥利平因 (cardiolipin) 是一种心脏蛋白质.卡斯帕斯-11是一种在Caspase-4中使用.在LPS中使用LPS.非正规的炎症性细胞组

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