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在感染性休克患者中减少非复苏液的协议化减少. 减少随机临床试验的协议

Peter Bentzer^1,2, Anja Lindén^1,3, Markus H Olsen^4,5

¹Anesthesiology and Intensive Care, Department of Clinical Sciences Malmö, Lund University, Lund, Sweden.

Acta anaesthesiologica Scandinavica

|July 17, 2025

概括

在败血性休克患者中限制非复苏液体可能会改善结果. 这项临床试验将限制性液体给药与通常护理进行比较,评估死亡率和并发症.

科学领域:

关键护理医学关键护理医学
腎臟病學 (nephrology) 是一種醫學專業.
环境健康环境健康

背景情况:

在败血症休克中,大量的液体与患者不良结果有关.
非复苏液体在重症监护室 (ICU) 中是一个重要的,可修改的液体来源.

研究的目的:

为了测试限制性非复苏液的管理是否改善了与通常护理相比,败血性休克患者的结果.
评估不同流体管理策略对气候的影响.

主要方法:

在ICU中患有败血性休克的成年患者将在入院12小时内随机分配到协议化限制性非复苏液体或通常的护理.
主要结局是90天全因死亡率.
二次结果包括ICU并发症,无机械通风的日子,以及长期的认知功能和生活质量.

主要成果:

本部分应在研究完成后填写.

结论:

本部分应在研究完成后填写.

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