在患有高出血风险的患者中,在左心室尾闭塞后停止抗血栓治疗
Siu-Fung Wong1, James W McCready1, James Cockburn1
1Department of Cardiology, Sussex Cardiac Centre, University Hospitals Sussex, Brighton, UK.
概括
在左心房尾闭塞 (LAAO) 后6个月停止抗血栓治疗对于高出血风险患者是安全的. 这种方法显示,手术后中风或过渡性缺血性发作 (TIA) 的发生率很低.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 血栓形成研究研究
背景情况:
- 抗血栓治疗对于装置内皮化来说,对左心房附属体封闭后 (LAAO) 的治疗至关重要.
- 接受LAAO的患者往往有高出血风险,使最佳的抗血栓策略成为临床挑战.
研究的目的:
- 为了评估最长6个月的抗血栓治疗时间在高出血风险的心房患者在LAAO后的疗效.
- 在这个患者队列中评估缩短抗血栓治疗方案的安全性和有效性.
主要方法:
- 在2015-2024年期间治疗的128名LAAO患者的回顾性分析.
- 患者在手术后接受了最长6个月的抗血栓治疗.
- 监测了包括中风,过时性缺血性攻击 (TIA),严重出血和死亡在内的结果.
主要成果:
- 该研究包括128名患者,其中许多患者先前有出血事件 (82.8%) 或中风 (60.9%).
- 实现了高的关闭率 (90.6%). 卒中/TIA发病率为5.5% (1.45/100患者年),显著减少了预测风险.
- 严重出血发生在10.2% (2.69/100患者年),死亡率为36.7% (9.71/100患者年).
结论:
- 在LAAO后6个月完全停止抗血栓治疗,与中风和TIA的发病率较低有关.
- 这种策略对于接受LAAO的高出血风险患者来说似乎是有效和安全的.
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