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相关概念视频

REM Sleep Behavior Disorder01:15

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REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
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Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol
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使用功能神经成像评估儿童睡眠呼吸障碍执行功能.

Nithya Navarathna1,2, Sergio L Novi1, Sophia Uddin1

  • 1Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
|July 17, 2025
PubMed
概括
此摘要是机器生成的。

这项研究表明,功能近红外光谱学 (fNIRS) 可以评估睡眠呼吸障碍 (SDB) 的儿童的大脑活动. 患有SDB的儿童前额叶皮层活化减少与症状严重程度和执行功能障碍相关.

关键词:
行为行为行为行为行为.执行职能 执行职能是指执行职能.功能近红外光谱学近红外光谱学儿科睡眠呼吸障碍 儿童睡眠呼吸障碍前额叶皮层前额叶皮层.

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科学领域:

  • 儿科神经学 儿科神经学
  • 神经成像是一种神经成像.
  • 睡眠医学 睡眠医学

背景情况:

  • 睡眠呼吸障碍 (SDB) 影响10%的儿童,与注意力和执行功能缺陷有关.
  • 在学龄儿童中,SDB对认知的影响的神经机制尚不清楚.
  • 功能磁共振成像 (fMRI) 对于这个年龄组来说是具有挑战性的,因为运动器件.

研究的目的:

  • 评估功能近红外光谱学 (fNIRS) 的可行性,以评估SDB儿童前额叶皮层 (PFC) 激活.
  • 调查SDB症状负担,执行功能和PFC活动之间的关系.
  • 探索fNIRS作为儿童友好的神经成像工具,用于儿科SDB研究.

主要方法:

  • 一项前性观察性研究,涉及78名患有SDB的儿童 (5-11岁).
  • fNIRS在Go/No-Go任务评估响应抑制时记录了PFC活动.
  • 儿童睡眠问卷和行为评分执行功能清单 (BRIEF) 评估了SDB症状和执行功能.

主要成果:

  • 较大的SDB症状负担与减少的PFC激活相关 (r = -0.31,P = .028在左中额头).
  • 较高的执行功能障碍得分与多个地区较低的PFC激活有关.
  • 左背侧PFC激活调节了SDB-症状-执行功能关系,表明潜在的神经补偿.

结论:

  • 基于任务的fNIRS是研究儿童SDB神经相关的可行方法.
  • SDB症状对PFC激活产生负面影响,可能会调解行为效应.
  • fNIRS提供了一种实用的方法来研究小儿SDB中的大脑功能.