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Updated: Sep 15, 2025

Profiling Ubiquitin and Ubiquitin-like Dependent Post-translational Modifications and Identification of Significant Alterations
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Profiling Ubiquitin and Ubiquitin-like Dependent Post-translational Modifications and Identification of Significant Alterations

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对O6 - - 甲基-2'-脱氧氨酸结合蛋白的全蛋白体识别

Andrew H Kellum1, Michelle Y Wang1,2, Ting Zhao3

  • 1Department of Chemistry, University of California Riverside, Riverside, California 92521-0403, United States.

Analytical chemistry
|July 17, 2025
PubMed
概括

研究人员确定了识别O6-甲基-2'-脱氧氨酸 (O6-Me-dG) DNA损伤的蛋白质. 丢失CDKN2AIP (CARF) 蛋白增加了对DNA甲基化剂的敏感性,揭示了它在DNA损伤反应中的作用.

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相关概念视频

Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
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