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Updated: Sep 15, 2025

Describing a Transcription Factor Dependent Regulation of the MicroRNA Transcriptome
07:23

Describing a Transcription Factor Dependent Regulation of the MicroRNA Transcriptome

Published on: June 15, 2016

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miR-34a结合点的序列,结构和亲缘关系决定了抑制功效

Lara Sweetapple1, David M Kosek2,3, Elnaz Banijamali1

  • 1Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm 17177, Sweden.

Nucleic acids research
|July 17, 2025
PubMed
概括

与阿尔戈诺特 (AGO) 蛋白结合的微RNA (miRs) 影响基因表达. 这项研究揭示了mRNA:miR结构和AGO2结合如何影响抑制效率,确定了超出简单结合亲和力的关键因素.

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