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Updated: Sep 15, 2025

Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions
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Author Spotlight: A Computational Approach to Decipher Amino Acid Preferences in Multispecific Protein-Protein Interactions

Published on: January 26, 2024

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使用三胞胎残留物预测纳米体结合的相互作用热点

Rahma Hamdani1, Damiano Cianferoni1, Raul Reche1

  • 1Department of Systems and Synthetic Biology, Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain.

Protein science : a publication of the Protein Society
|July 17, 2025
PubMed
概括

一个新的算法预测了蛋白质-蛋白质相互作用 (PPI) 的纳米体设计中的结合热点. 这种工具有助于开发有针对性的纳米体疗法,通过识别用于改进药物设计的关键残留物.

关键词:
具有约束力的热点.计算预测的计算预测.发现药物的发现.纳米体是一种纳米体.蛋白质蛋白质相互作用结构生物学结构生物学

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Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues07:08

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