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开发和验证一种基于LASSO的诺米克图,用于预测腹腔镜胃切除术后老年患者的门泄漏

Na Yang¹, Ying Deng²

¹Department of Thoracic Surgery, Shengjing Hospital of China Medical University, Shenyang, China.

Journal of gastrointestinal oncology

|July 17, 2025

概括

这项研究开发了一种名谱,用于预测老年患者的腹腔镜胃切除术 (LG) 后的解肠流漏 (AL). 该模型使用年龄,ASA得分,糖尿病,血液损失和PNI用于早期风险识别和预防.

科学领域:

手术瘤学手术瘤学
胃肠道手术胃肠道手术
老年医学老年医学

背景情况:

解剖漏 (AL) 是腹腔镜胃切除术 (LG) 的一个关键的术后并发症.
在接受LG的老年患者中早期识别AL是具有挑战性的.
在这个人群中,AL会导致危及生命的结果.

研究的目的:

开发和验证一种风险预测模型,用于在接受LG的老年患者中早期识别AL.
创建一个包含关键周周操作变量的名录.
改善针对AL的预防策略.

主要方法:

对884名接受LG治疗的老年患者进行了回顾性分析.
使用LASSO和多变量逻辑回归开发一个名图.
使用AUC,Hosmer-Lemeshow测试,校准曲线和DCA,验证名录的验证.

主要成果:

关节炎的发生率为13.6%.
独立预测AL的预测因素包括年龄,ASA得分,糖尿病,手术期间流血和PNI.
诺米图表显示了高的预测准确性 (AUC 0.870-0.890) 和临床效用.

结论:

一个LASSO衍生名图可靠地预测老年LG患者的AL风险.
该模型结合了常规评估的术后变量.
早期风险识别有助于针对性预防干预.

关键词:

解剖学性泄漏 (AL) 的情况年长的老人老年人老年人.腹腔镜胃切除术 (LG) 是一种腹腔镜胃切除术.这个名字是名ogramogram.预测模型预测模型

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