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Updated: Sep 15, 2025

Detecting Cortex Fragments During Bacterial Spore Germination
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一种新的细菌分泌机制,基于编程的二甲糖降解

Carlos A Ramírez Carbó1,2, Oihane Irazoki3, Srutha Venkatesan1

  • 1Department of Biology, Texas A&M University, College Station, Texas, USA.

bioRxiv : the preprint server for biology
|July 17, 2025
PubMed
概括

Myxococcus xanthus 细菌在没有细胞分裂的情况下形成子,依赖于酸甘油 (PG) 细胞壁降解由性转糖酶 (LTGs). LtgB 调节 LTG 活动以控制子,防止有缺陷的子形成.

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Sporulation is a complex developmental process that allows certain Gram-positive bacteria, such as Bacillus subtilis and Clostridium species, to survive extreme environmental conditions. This process is tightly regulated by a series of signaling cascades and transcriptional controls, ensuring the formation of a highly resistant endospore.Sporulation is triggered by unfavorable conditions, such as nutrient depletion, and is governed by a phosphorelay system. One of the sensor kinases, such as...
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Endospores are specialized, dormant cells primarily formed by Gram-positive bacteria, including Bacillus and Clostridium, enabling survival under extreme environmental conditions. Due to their unique composition and formation process, these structures are highly resistant to physical and chemical insults, such as extreme heat, ultraviolet and ionizing radiation, desiccation, and toxic chemicals. Rare instances of endospore-like structures have also been observed in some Gram-negative bacteria,...
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Coordination of Gene Expression Processes in Bacteria

The DNA replication, transcription, and translation processes are intricately coupled in bacteria, allowing efficient gene expression and rapid protein synthesis. While this physical and functional coordination is advantageous, it introduces challenges that bacteria overcome through specific regulatory mechanisms.Coupling of Replication, Transcription, and TranslationThe coupling of replication, transcription, and translation is a hallmark of bacterial gene expression. As the replisome unwinds...
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