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Updated: Sep 15, 2025

Murine Dermal Fibroblast Isolation by FACS
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Murine Dermal Fibroblast Isolation by FACS

Published on: January 7, 2016

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一个纤维细胞状态编排了一种依赖于YAP的表皮细胞再生程序,通过ECM介导的机械传导对 (前) 恶性瘤至关重要

Deng Pan, Philippe Gascard, Joseph A Caruso

    bioRxiv : the preprint server for biology
    |July 17, 2025
    PubMed
    概括

    慢性肺损伤会触发一种亲瘤原生纤维细胞状态 (STIF),从而导致转化成形和发育不良. 抑制这种压力/张力指导性纤维细胞信号传递可以预防或逆转这些癌前变化,提供新的预防策略.

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