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Updated: Sep 15, 2025

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
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在阿尔茨海默氏症疾病中的上下文依赖的调节变异

Ziheng Chen, Yaxuan Liu, Ashley R Brown

    bioRxiv : the preprint server for biology
    |July 17, 2025
    PubMed
    概括

    在晚发性阿尔茨海默病 (LOAD) 中识别非编码基因变异是具有挑战性的. 这项研究使用了大量并行记者分析和机器学习,揭示了变异如何在细胞类型和状态之间不同影响基因调节.

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