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Updated: Sep 15, 2025

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包括z-链驱动CD19-CAR T细胞中的色素信号传递

Aurora Callahan, Ryan Z Puterbaugh, Timothy Ro

    bioRxiv : the preprint server for biology
    |July 17, 2025
    PubMed
    概括

    ζ 链决定了嵌合式抗原受体 (CAR) T 细胞的信号传递,而不管如何进行刺激. 抑制Itk可能会阻止抗原独立的CAR T细胞激活,提高治疗安全性.

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