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Updated: Sep 15, 2025

Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4+CD45RBhigh T Cells into Immunodeficient Mice
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Published on: April 21, 2015

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大肠炎的循环T细胞通过Nod2,微生物群和肌光链激酶依赖的机制驱动小肠道屏障功能

Arthur Mauduit, Talal Nabhani, Luisa Morelli

    bioRxiv : the preprint server for biology
    |July 17, 2025
    PubMed
    概括

    结肠炎症通过Nod2-MLCK-CD4+ T细胞通路破坏小肠障碍物功能. 向肌素轻链激酶 (MLCK) 恢复屏障完整性,并减少炎症性肠道疾病 (IBD) 的炎症.

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