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Updated: Sep 15, 2025

Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
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在内皮细胞中对ERK5转录活性进行TNIK驱动的调节

Venkata Subrahmanya Kumar Samanthapudi1, Sivareddy Kotla1, Nhat-Tu Le2

  • 1Department of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

Frontiers in cardiovascular medicine
|July 17, 2025
PubMed
概括

交互Traf2和Nck激酶 (TNIK) 调节细胞外信号调节激酶5 (ERK5) 信号传递,影响血管平衡. TNIK通过MEK5依赖和独立的途径调节ERK5的转录活性,为血管疾病提供治疗潜力.

关键词:
在ERK5中,ERK5是ERK5.这就是TNIK TNIK.它们是内皮细胞的内皮细胞.这是一种炎症炎症炎症炎症.转录活动转录活动.

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