夜,抑郁症和认知功能之间的关系以及老年人营养指数的调解效应:来自NHANES 2011-2014年的数据
Yin Xu1, Xinmei Wang2, Guofeng Wang1
1Department of Gerontology, The 960th Hospital of PLA, Jinan, China.
Frontiers in nutrition
|July 17, 2025
概括
夜与老年人,特别是女性的抑郁和认知能力下降有关. 像白蛋白和血红蛋白这样的营养因素起着作用,这表明饮食改善可能会降低夜尿风险.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 营养科学 营养科学
背景情况:
- 夜,抑郁和认知功能是老龄化人口的重大健康问题.
- 了解这些条件和潜在的调解因素之间的相互作用对于有效的干预至关重要.
研究的目的:
- 调查老年人夜,抑郁症和认知功能之间的相关性.
- 检查白蛋白和血红蛋白在这些关系中的调解作用.
主要方法:
- 来自国家健康和营养检查调查 (2011-2014) 数据的分析.
- 使用多重逻辑回归来进行统计分析.
- 按性别分层分析以确定特定性别的相关性.
主要成果:
- 夜风险与认知功能得分 (数字符号得分 - DSS) 和抑郁症得分 (患者健康问卷 - PHQ-9) 有显著的相关性.
- 与男性相比,女性在动物流利性得分 (AFS),DSS,PHQ-9和夜尿风险之间表现出更强的相关性.
- 白蛋白和血红蛋白部分介导了认知/抑郁分数和夜风险之间的关联,性别的影响有所不同.
结论:
- 夜与老年人,尤其是女性的抑郁和认知障碍有积极的关联.
- 通过白蛋白和血红蛋白水平表示的营养状况,部分调解了这些关联.
- 旨在改善营养状况的干预措施可能有助于减轻老年人夜尿风险.
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