使用贝叶斯空间元回归方法,确定热浪与早产之间的联系的县级效应修饰者
Shuqi Lin1, Howard H Chang2, Lyndsey A Darrow3
1Department of Biostatistics, Yale School of Public Health, Yale University, New Haven, CT.
medRxiv : the preprint server for health sciences
|July 17, 2025
概括
极端的高温会增加早产的风险,特别是在弱势群体中. 住房质量和社会脆弱性等因素改变了这些与热量相关的风险,突出了公共卫生干预的领域.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 生物统计学 生物统计学
背景情况:
- 高温对健康构成重大风险,尤其是孕妇和胎儿.
- 现有的关于热量和早产的研究缺乏对空间变化和修饰因素的关注.
研究的目的:
- 估计美国八个州热浪和早产之间的县级关联.
- 通过空间元回归来探索修改热浪和早产相关的县级因素.
主要方法:
- 采用了两阶段的建模方法.
- 层次贝叶斯空间元回归,结合条件自回归模型,被用来解释空间依赖.
- 开发了一个R包,SpMeta,用于合成区域级风险估计.
主要成果:
- 观察到与热浪相关的早产风险具有显著的空间异质性.
- 住房质量,能源负担能力和社会脆弱性 (少数群体地位,语言障碍) 等因素被确定为这些风险的重大变化因素.
结论:
- 与热浪相关的早产风险在空间上有所不同,受社会经济和环境因素的影响.
- 识别和解决这些可修改的因素对于减轻脆弱人群中不良出生结果至关重要.
相关概念视频
Statistical Methods for Analyzing Epidemiological Data
540
Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
540
Regression Toward the Mean
6.5K
Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when...
6.5K
Quantifying Heat
56.2K
Thermal Energy Microscopically, thermal energy is the kinetic energy associated with the random motion of atoms and molecules. Temperature is a quantitative measure of “hot” or “cold”, which depends on the amount of thermal energy. When the atoms and molecules in an object are moving or vibrating quickly, they have a higher average kinetic energy (KE) (or higher thermal energy), and the object is perceived as “hot”, or it is described as being at a...
56.2K
Bias in Epidemiological Studies
695
Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:
695
Confounding in Epidemiological Studies
266
Confounding in statistical epidemiology represents a pivotal challenge, referring to the distortion in the perceived relationship between an exposure and an outcome due to the presence of a third variable, known as a confounder. This variable is associated with both the exposure and the outcome but is not a direct link in their causal chain. Its presence can lead to erroneous interpretations of the exposure's effect, either exaggerating or underestimating the true association. This...
266
Regression Analysis
6.1K
Regression analysis is a statistical tool that describes a mathematical relationship between a dependent variable and one or more independent variables.
In regression analysis, a regression equation is determined based on the line of best fit– a line that best fits the data points plotted in a graph. This line is also called the regression line. The algebraic equation for the regression line is called the regression equation. It is represented as:
In regression analysis, a regression equation is determined based on the line of best fit– a line that best fits the data points plotted in a graph. This line is also called the regression line. The algebraic equation for the regression line is called the regression equation. It is represented as:
6.1K


