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Updated: Sep 15, 2025

Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal
08:01

Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal

Published on: May 30, 2012

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在小鼠胚胎干细胞中通过多复合体1调节PKCi介导的多能性和基因表达

Fangfang Wu1, Zhihui Liu1, Xiaohu Wu1

  • 1Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University Nanjing 210046, Jiangsu, China.

American journal of translational research
|July 17, 2025
PubMed
概括

蛋白激酶C抑制 (PKCi) 通过激活Polycomb抑制复合体1 (PRC1) 途径来维持小鼠胚胎干细胞 (mES) 的多能性. 这种表观遗传调节平衡了自我更新和分化,这对干细胞研究至关重要.

关键词:
胚胎干细胞是一种胚胎干细胞.抑制PKC的抑制作用在PRC1中,表观遗传学是指表观遗传学.这里是鼠标鼠标鼠标鼠标鼠标鼠标.这是一个多重复合材料.

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