低剂量氨酸对近视进展的儿童胸腔厚度的影响
Shrutakirty Parida1, Matuli Das2, Snehalata Dash3
1Pediatric Ophthalmology, Strabismus and Neuro-ophthalmology, Kalinga Institute of Medical Sciences, Bhubaneswar, IND.
Cureus
|July 17, 2025
概括
低剂量阿特罗平 (0.01%) 在渐进近视的儿童中显著增加了胆道厚. 这种冠状腺厚与近视进展缓慢相关,表明潜在的治疗益处.
科学领域:
- 眼科医生 眼科 眼科
- 儿科眼科医生 儿科眼科医生
- 控制近视 控制近视
背景情况:
- 渐进的近视是儿童日益关注的问题.
- 冠状腺厚度是近视进展的潜在生物标志物.
- 低剂量氨酸正在研究近视控制.
研究的目的:
- 为了评估0.01%低剂量阿特罗宾对渐进性近视儿童胸膜厚度的影响.
- 为了比较低剂量氨酸和安慰剂组之间的近视进展率.
- 评估折射误差,轴长 (AXL) 和最佳校正视敏度 (BCVA) 的变化.
主要方法:
- 一个前性的,病例控制干预研究.
- 87名患有双边渐进近视的儿童 (5-16岁) 被随机分为两组.
- 测量包括基线和6个月的球体等价值,AXL和胸膜厚度;一组接受了低剂量类药物,另一组接受了安慰剂.
主要成果:
- 低剂量阿特罗平在3个月和6个月后显著增加了整体胆道厚度.
- 冠状腺厚度的增加与近视进展缓慢的显著相关性 (球形等效和AXL).
结论:
- 低剂量阿特罗平 (0.01%) 有效地诱导慢性近视的儿童胆道结厚.
- 这种冠状腺的加厚与近视的进展率降低有关.
- 低剂量氨酸显示出作为治疗近视控制的治疗干预的潜力.
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