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Updated: Sep 15, 2025

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
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图形卷积神经网络启用边界分子轨道预测:一个用神经递质和抗抑郁药物的案例研究

Rivaaj Monsia1, Stewart C Gundry1, Molly L Mohr1

  • 1Department of Chemistry and Biochemistry, University of Wisconsin─Eau Claire, Eau Claire, Wisconsin 54702, United States.

Journal of chemical information and modeling
|July 17, 2025
PubMed
概括

人工智能准确地预测了与大脑受体的神经化学相互作用. 这项研究使用图形卷积神经网络人工神经网络 (GCN-ANN) 来揭示化学硬度如何影响结合亲和力,有助于开发向抗抑郁药物.

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