在注射药物的人中,患者对感染性内心炎的替代抗生素治疗策略的看法
Journal of addiction medicine
|July 17, 2025
概括
由于注射药物使用而患有传染性内心炎 (IE) 的患者更喜欢标准住院治疗而不是门诊抗生素选择. 交通和住房不稳定等障碍阻碍了接受与药物使用相关的替代性IE治疗.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 注射药物使用是感染性内心炎 (IE) 的重要和不断增加的风险因素.
- 目前与药物使用相关的IE (DUA-IE) 的标准治疗包括长期的住院抗菌疗法.
- 正在探索替代抗生素输送方法,但患者接受度尚不清楚.
研究的目的:
- 探索患者的偏好,并确定不同DUA-IE治疗策略的障碍/促进因素.
- 了解患有DUA-IE的个体对拟议的治疗选择的看法.
主要方法:
- 半结构面试对16名因DUA-IE住院的患者进行了半结构面试.
- 参与者讨论了三种治疗方案:标准住院护理,家庭门诊亲肠道抗菌药物治疗和每周门诊输液.
- 采访被主题编码,以分析参与者的观点.
主要成果:
- 标准住院治疗 (选项A) 是最喜欢的方案 (50%).
- 31%的人更喜欢每周的门诊输液 (选项C),19%的人更喜欢家庭治疗 (选项B).
- 虽然门诊选择提供了方便,但交通和住房不稳定是主要障碍.
结论:
- 患者的观点对于设计未来的DUA-IE治疗试验至关重要.
- 针对以患者为中心的需求和障碍的干预措施是有效的DUA-IE管理所必需的.
- 了解患者的偏好可以为开发可接受和有效的替代治疗策略提供信息.
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