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Updated: Sep 15, 2025

Come to the Light Side: In Vivo Monitoring of Pseudomonas aeruginosa Biofilm Infections in Chronic Wounds in a Diabetic Hairless Murine Model
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高血糖抑制的Acod1表达有助于在Pseudomonas aeruginosa角质炎中导致先天性免疫缺陷

Nan Gao1, Rao Me1, Sukhvinder Singh1

  • 1Departments of Ophthalmology and Anatomy and Cell Biology, Kresge Eye Institute, Wayne State University School of Medicine, Detroit, Michigan, United States.

Investigative ophthalmology & visual science
|July 17, 2025
PubMed
概括

在糖尿病小鼠中抗击细菌角膜炎时,甲酸脱碳酶1 (Acod1) 和伊塔科纳酸是必不可少的. 基于伊塔科纳酸的疗法在糖尿病患者治疗眼部感染方面表现有前途.

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Gene Regulation in Microbial Communities: Quorum Sensing01:28

Gene Regulation in Microbial Communities: Quorum Sensing

Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
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