外科医生进行的口腔超声学,用于检测和分期口腔癌
Martin Garset-Zamani1,2, Gitte Bjørn Hvilsom3, Thomas Kjærgaard4
1Department of Otorhinolaryngology, Head and Neck Surgery, and Audiology, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
JAMA otolaryngology-- head & neck surgery
|July 17, 2025
概括
与临床检查或MRI相比,超声波显著改善了口腔状细胞癌 (OPSCC) 的诊断. 这种方法为早期OPSCC检测提供了更高的准确性和诊断确定性.
科学领域:
- 在瘤学瘤学.
- 诊断成像 诊断成像 诊断成像
- 头部和部手术 头部和部手术
背景情况:
- 早期口腔状细胞癌 (OPSCC) 诊断是当前临床检查和横截面成像的挑战.
- 横腔超声波提供高分辨率成像,但其对OPSCC的诊断实用性尚未确立.
- 迫切需要改善OPSCC的早期检测和T分期.
研究的目的:
- 为了比较临床检查,超声波和磁共振成像 (MRI) 检测口腔瘤的诊断准确度.
- 评估超声波在改善疑似OPSCC的诊断评估方面的有效性.
主要方法:
- 一个多中心诊断临床试验,涉及162名疑似OPSCC的患者.
- 通过外科医生进行的横口和横超声波检查与临床检查和MRI进行了比较.
- 组织病理学作为口腔喉瘤存在的参考标准.
主要成果:
- 与临床检查 (68%) 和MRI (76%) 相比,超声波显示的整体诊断准确度显著更高 (86%).
- 瘤检测的灵敏度在各种方法中是相似的 (超声波90%,临床检查82%,MRI92%).
- 与临床检查 (41%) 和MRI (46%) 相比,在没有瘤的患者中,超声波显示出明显更高的特异性 (79%).
结论:
- 通过外科医生进行的横口和横超声波检查为怀疑的OPSCC提供了比临床检查和MRI更高的诊断准确度.
- 超声波增强了怀疑口腔瘤的临床评估,提供了更大的诊断确定性.
- 这种技术对于改善OPSCC的早期检测和T分期非常有价值.
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