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Updated: Sep 15, 2025

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity
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Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity

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侵略性的B细胞淋巴瘤保留了ATR依赖的T细胞排除在生殖中心黑暗区的ATR决定因素

Valeria Cancila1, Giorgio Bertolazzi2, Allison Sy Chan3

  • 1Tumor Immunology Unit, Department of Health Sciences, University of Palermo, Palermo, Italy.

The Journal of clinical investigation
|July 17, 2025
PubMed
概括

研究人员发现,抑制ATR逆转了生殖中心黑暗区域的T细胞排斥. 这种免疫沉默机制可能是针对增强T细胞免疫疗法对攻击性淋巴瘤的目标.

关键词:
细胞生物学 细胞生物学免疫学 免疫学 免疫学淋巴瘤是一种淋巴瘤.分子病理学分子病理学在瘤学瘤学.在T细胞,T细胞.

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