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Updated: Jul 21, 2026

Intravital Microscopy Imaging of the Liver following Leishmania Infection: An Assessment of Hepatic Hemodynamics
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使用代谢分析在小鼠Leishmania感染期间识别免疫媒介的协议

Thalia Pacheco-Fernandez1, Laura Klenow1, Nazli Azodi1

  • 1Division of Emerging and Transfusion Transmitted Diseases, Office of Blood Research and Review, Center of Biologics Research and Evaluation, Food and Drug Administration, Silver Spring, MD 20993, USA.

STAR protocols
|July 17, 2025
PubMed
概括

本研究概述了一项协议,用于识别使用代谢分析和质谱的莱什曼尼亚感染小鼠的免疫媒介. 该方法有助于了解宿主对感染的免疫反应.

关键词:
质谱测量质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量代谢生物组的代谢生物组微生物学的微生物.模型生物模型生物.分子生物学分子生物学

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Antiprotozoal Agents01:21

Antiprotozoal Agents

Leishmaniasis is a widespread parasitic disease caused by several Leishmania species. It affects millions of people each year and remains a major public health problem in endemic regions. First-line treatment relies on pentavalent antimonials, including meglumine antimoniate and sodium stibogluconate. Even so, how these drugs work has not been fully clear, especially their interaction with parasite-specific biochemical pathways. One key target is trypanothione reductase (TR), an enzyme that...